and then adding acid-base neutralization to return to the parent molecular state. Because activated carbon does not adsorb ions,cbd centrifugal extractor, the product loss caused by activated carbon adsorption is negligible. Neutralization extraction method: It is a common method in industrial processes and laboratories. It uses the characteristics that acid-base organic compounds are dissolved in water when they generate ions and the parent molecules are dissolved in organic solvents. By adding acids and bases, the parent compounds generate ions and dissolve in water to achieve phase transfer, and non-water-soluble organic solvents are used to extract non-acid-base impurities. Dissolving in an organic solvent to separate the impurities from the product. Salification method: for water-insoluble macromolecular organic ionic compounds, organic acidic and alkaline compounds can be salted and crystallized in the organic solvent, while non-salifying impurities remain in the organic solvent, thus realizing the separation of organic acidic and alkaline compounds from non-acidic and alkaline impurities. Acidic and alkaline organic impurities can be separated by recrystallizing the precipitated crystals. The salt of the organic acid and base compound of the macromolecule can also be washed by water to remove the impurities of the acid and base compound of the micromolecule which has been salted and has water solubility. In the case of water-soluble organic ionic compounds, impurities can be separated from the product by forming a salt in water, removing the water by azeotropic distillation or direct distillation, and thoroughly washing the residue several times with an organic solvent. The above three methods are not isolated. According to the nature of the compound and the requirements of the product quality standards, a combination of methods can be used to obtain products of considerable purity as far as possible. (2) Several special organic extraction solvents: N-butanol: Most small alcohols are water-soluble, such as methanol, ethanol, isopropanol, n-propanol, etc. Most high molecular weight alcohols are insoluble in water, but are lipophilic and soluble in organic solvents. However, the intermediate alcohol solvent, such as n-butanol, is a good solvent for machine extraction. N-butanol itself is insoluble in water, and it has the common characteristics of small molecular alcohol and large molecular alcohol. It can dissolve some polar compounds that can be dissolved by small molecular alcohols, while it is insoluble in water. Using this property, n-butanol can be used to extract polar reaction products from aqueous solutions. Butanone: Properties intermediate between small and large ketones. Unlike acetone, which is soluble in water, butanone is insoluble in water and can be used to extract the product from water. Butyl acetate: The property is between small molecule and macromolecule ester. Its solubility in water is very small, unlike ethyl acetate, which has a certain solubility in water. It can extract organic compounds from water, especially amino acid compounds. Therefore, it is commonly used in the antibiotic industry to extract cephalosporin, penicillin and other macromolecular compounds containing amino acids. Isopropyl ether and tert-butyl ether: The properties are between small molecular ether and large molecular ether, decarboxylation after extraction ,winterization filtration, the polarity of both is relatively small, similar to n-hexane and petroleum ether, and the solubility of both in water is small. The system that is difficult to decolorize can be removed by silica gel and alumina. It is sometimes difficult to decolorize acidic and alkaline compounds. When acidic compounds are neutralized with alkali to form ionic compounds and dissolved in water for decolorization, in addition to decolorizing once to remove alkaline impurities under weak alkaline conditions, the system should be gradually neutralized to weak acidity, and then decolorized once to remove acidic impurities, so that the pigment can be completely removed. Similarly,cbd crystallization equipment, when the alkaline compound is neutralized with acid until it is weakly alkaline and dissolved in water for decolorization, in addition to decolorizing once to remove acidic impurities under weakly acidic conditions, the system should be gradually neutralized to weakly alkaline and then decolorized once again to remove alkaline impurities. (Source: Internet) (Photo: Pixabay) Back to Sohu to see more Responsible Editor:. toptiontech.com
